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Seroquel

Generic Seroquel (Quetiapine)

Seroquel is an oral antipsychotic drug to treat major depressive disorder, schizophrenia and bipolar disorder.
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25mg
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Seroquel $48.00
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25mg
60pills
Seroquel $77.00
$63.99
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25mg
90pills
Seroquel $103.00
$85.99
$0.96 per pill
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25mg
120pills
Seroquel $124.00
$102.99
$0.86 per pill
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25mg
180pills
Seroquel $168.00
$139.99
$0.78 per pill
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25mg
360pills
Seroquel $301.00
$250.99
$0.70 per pill
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50mg
30pills
Seroquel $62.00
$51.99
$1.73 per pill
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50mg
60pills
Seroquel $100.00
$82.99
$1.38 per pill
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50mg
90pills
Seroquel $134.00
$111.99
$1.24 per pill
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50mg
120pills
Seroquel $161.00
$133.99
$1.12 per pill
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50mg
180pills
Seroquel $217.00
$180.99
$1.01 per pill
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100mg
30pills
Seroquel $91.00
$75.99
$2.53 per pill
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100mg
60pills
Seroquel $146.00
$121.99
$2.03 per pill
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100mg
90pills
Seroquel $198.00
$164.99
$1.83 per pill
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100mg
120pills
Seroquel $238.00
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$1.65 per pill
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100mg
180pills
Seroquel $320.00
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200mg
30pills
Seroquel $161.00
$133.99
$4.47 per pill
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200mg
60pills
Seroquel $257.00
$213.99
$3.57 per pill
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200mg
90pills
Seroquel $346.00
$287.99
$3.20 per pill
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200mg
120pills
Seroquel $415.00
$345.99
$2.88 per pill
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300mg
30pills
Seroquel $203.00
$168.99
$5.63 per pill
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300mg
60pills
Seroquel $324.00
$269.99
$4.50 per pill
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300mg
90pills
Seroquel $438.00
$364.99
$4.06 per pill
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Special patient populations. If you miss a dose, you should take it as soon as possible, unless it is already time for your next dose. Children and Adolescents ages 10 to 17 : Nausea, dry mouth, weight gain, increase appetite, vomiting, and rapid heartbeat. Physicians may recommend a reduced dose for adults over age 65 or people with liver problems. Your doctor will watch you carefully for any of these symptoms when you start Seroquel. Mechanism of action. Seroquel should be administered once daily at bedtime. Increases in triglyceride levels and total cholesterol predominantly LDL cholesterol have been observed during treatment with quetiapine. Prescriptions for quetiapine should be written for the smallest quantity of tablets consistent with good patient management in order to reduce the risk of overdose. Quetiapine should be used with caution in patients receiving medications having anti-cholinergic muscarinic effects. Earlier this year, the company agreed to sell the rights to the two antidepressant drugs in Europe except the UK and Russia to Cheplapharm. Can symptoms occur if Seroquel is discontinued? Remember to always consult your physician or health care provider before starting, stopping, or altering a treatment or health care regimen. Seroquel 25 mg, peach, round, film Sedoquel. Serious side effects can occur. Consideration Segoquel be given to changing the therapeutic regimen, Seroauel possibly discontinuing the medication, in patients whose depression is persistently worse, or who are experiencing emergent suicidality or symptoms that might be precursors to worsening depression or suicidality, especially if these symptoms are severe, abrupt in onset, or were not part of the patient's presenting symptoms. There are no consistent adverse events that have been reported in infants exposed to quetiapine through breast milk. Seroquel has no habit-forming potential, but it is not recommended that you discontinue use of the drug before talking with your doctor, as withdrawal symptoms can occur. It is used to treat conditions such as:. Medications that inhibit or induce CYP3A4, an enzyme that metabolizes certain drugs, can increase or decrease how the body absorbs Seroquel. Drug-Drug Interaction Studies The in vivo assessments of effect of other drugs on the pharmacokinetics of quetiapine are summarized in Table 17 [see Dosage and Administration 2. Drug Label Information Updated January 7, If you are a consumer or patient please visit this version. As improvement may not occur during the first few weeks or more of treatment, patients should be closely monitored for clinical worsening and suicidality, especially at the beginning of a course of treatment or at the time of dose changes, either increases or decreases. Ask your doctor about the risks and benefits involved. Common side effects include sleepiness, constipationweight gain, and dry mouth. Coalition of 62 nations backs Australian, EU push for coronavirus inquiry. Patients should be advised regarding appropriate care in avoiding overheating and dehydration [see Warnings and Precautions 5. Dose Schedules. Exclusive Corporate feature. Clinical trials. Learn how we develop our content. Quetiapine Fumarate slide 12 of 52, Quetiapine Fumarate. Views Read View Sefoquel View history. At high doses, quetiapine starts blocking significant amounts of dopamine receptors. Retrieved 20 October For people with low or high blood pressure: Quetiapine may worsen your high or low blood pressure.
Common use

Seroquel is an oral antipsychotic (neuroleptic) medication used for treating schizophrenia and acute manic episodes associated with bipolar I disorder. It shows more affinity with serotonin receptors (5-HT2) than with dopamine receptors D1 and D2 in the brain. It also active toward the alpha 1 adrenoreceptor and less active toward alpha 2 adrenoreceptor. Duration of binding with 5-HT2-serotonin and D2 dopamine receptors is less than 12 hours. Mechanism of Quetiapine action is unknown. Though it is supposed that the therapeutic effect is mediated through a combination of dopamine type 2 (D2) and serotonin type 2 (5HT2) receptor antagonism. This medication is used to treat acute and chronic psychosis also ones in patients with schizophrenia.



Dosage and direction

Seroquel should be taken twice or thrice daily with or without food with a full glass of water. Swallo the tablet whole, do not crush or chew an extended-release tablet. Daily dose of four first therapeutic days is 50 mg, 100 mg (second day), 200 mg (third day), 300 mg (fourth day). Starting from the fourth day the dosage should be adjusted to the level of effective one (which can reach 750 mg daily). In patients with liver or kidney failure initial dose is 25 mg/day increased gradually by 25-50 mg till the effective dose is reached. Take exactly as prescribed by your physician and do not exceed the recommended dose.



Precautions

This medication affects ability to high concentration of attention so it may affect your ability to drive a car or operate machinery. Before to take Seroquel notify your doctor if you have liver or kidney disease, heart disease, high blood pressure, heart rhythm problems, heart attack or stroke in history, a history of low white blood cell counts, a thyroid disorder, high cholesterol or triglycerides, a personal or family history of diabetes, trouble swallowing, as you may need your dosage to be adjusted or pass special safety tests for this medication.



Contraindications

Hypersensitivity, pregnancy, breastfeeding. Seroquel should be used with cautiousness in patients with hypotension, epilepsy and epileptic seizures in history. Seroquel may contribute to development of heart failure, pneumonia, sudden death, in older adults with conditions caused by dementia.



Possible side effect

Seroquel antagonism of adrenergic a1 receptors may explain the orthostatic hypotension observed with this drug. Most common and frequent adverse effects of Seroquel are headache, agitation, dizziness, drowsiness, weight gain and stomach upset. Long term use of this medication may cause irreversible tardive dyskinesia, a neurologic disease which consists of involuntary movements of the jaw, lips, and tongue. Other side effects concern nervous system: headache, anxiety, fatigue, hostility, agitation, insomnia, tremors, convulsions, depression, neuroleptic malignant syndrome (hyperthermia, muscle rigidity, altered mental status, the lability of the autonomic nervous system increased activity of CPK). Adverse effects of Quetiapine for cardiovascular system are: tachycardia, prolongation of the interval QT. Dryness of the oral mucosa, nausea, vomiting, abdominal pain, diarrhea or constipation, increased activity of "liver" transaminases, pharyngitis, rhinitis may also appear. Allergic reactions such as skin rash, eosinophilia are also not excluded.



Drug interaction

Phenytoin (Dilantin) and thioridazine (Mellaril) decrease absorption of Seroquel in intestines and decrease its effects. Seroquel interacts with narcotic pain relievers, medications for hypertension interact with and their activities add: oxycodone and acetaminophen (Percocet, Roxicet, Tylox, Endocet), barbiturates, alprazolam (Xanax), clonazepam (Klonopin), ethanol, prazosin (Minipress) and terazosin (Hytrin). Toxicity of Quetiapine may increase if it is co-administered with the drugs able to influence work of cytochrome P450 which is responsible for metabolism of Seroquel, these drugs are: ketoconazole (Nizoral), itraconazole (Sporanox), fluconazole (Diflucan), erythromycin, clarithromycin (Biaxin), nefazodone (Serzone), verapamil (Calan, Isoptin, Verelan), diltiazem (Cardizem, Tiazac, Dilacor).



Missed dose

Take the missed dose as soon as you remember. If it is almost time of your next dose just skip the missed dose and return to your schedule. Do not double dose this medication to make up the missed dose.



Overdose

If you took too much of Seroquel you may experience such symptomes: extreme drowsiness, fast heart rate, feeling light-headed, or fainting. If you suppose that took too much for this medication seek for immediate medical help.



Storage

Store Seroquel at room temperature, 15-30 C (59-86 F) away from sunlight, moisture, children and pets.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Antidepressants

Antidepressants are psychotropic substances that are used in depression treatment.
The drug works by:

  • Increasing disposition
  • Decreasing fatigue, apathy, anxiety
  • Relief of emotional tension
  • Improves mental activity
  • Normalization sleep and appetite

In a healthy human being which is not affected by depression antidepressants do not exert any positive effects. Although the above positive effects manifest all the antidepressants do have specific side-effects that may impair your daily life. For example a feeling of tiredness is a common side-effect in the beginning of the antidepressant therapy which passes within a few weeks. It is important to take the medicine even after you start feeling better. A consultation with you health care provider is necessary before stopping the treatment as for many antidepressants the treatment should be stopped gradually.

Different group of antidepressants currently exist among them are:

  • MAO inhibitors - monoamine oxidase inhibitors
    • Selective MAO inhibitors
    • Non-selective MAO inhibitors
  • Preparations that block neuronal reuptake of amines
    • Non-selective blockers of norepinephrine and serotonin reuptake
    • Selective serotonin reuptake inhibitors
    • Selective norepinephrine reuptake inhibitors
  • Monoamine receptors agonists