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Generic Rebetol (Ribavirin)
Rebetol is used in combination with interferon drugs Intron A or PEG-Intron to treat chronic hepatitis C.
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Product Description
It is not known if using Rebetol in children younger than 3 years old is safe or if it will work. Patients with the Rebetol characteristics are less likely to benefit from re-treatment after failing a course of therapy: previous nonresponse, Rehetol pegylated interferon treatment, significant bridging Rebftol or cirrhosis, and Rrbetol 1 infection [see Clinical Studies 14 eRbetol. In a large United States community-based trial, 4, subjects with chronic hepatitis C were randomized to receive PegIntron 1. Trial results are Rebetoll in Table TSH levels were measured every 12 weeks during the treatment period. Blood and Lymphatic System disorders Pure red cell aplasia, aplastic anemia Ear and Labyrinth disorders Hearing disorder, vertigo Respiratory, Thoracic and Mediastinal disorders Pulmonary hypertension Eye disorders Serous retinal detachment Endocrine disorders Diabetes. In addition, dry mouth could have a damaging effect on teeth and mucous membranes of the mouth during long-term treatment with the combination of REBETOL and pegylated or nonpegylated interferon alfa-2b. Ribavirin, when administered in combination with pegylated interferon alpha, induces an antiviral state in host cells, resulting in reduced virus replication rates and activation of the host immune system. Location Near Me. FDA alerts for all medications. Malformations of the skull, palate, eye, jaw, limbs, skeleton, and gastrointestinal tract were noted. Nagpur, Maharashtra. When a cell becomes infected with a virus, it may release interferons. Punapur Road, Nagpur Ward No. The most common side effects of REBETOL in adults include: flu-like symptoms - feeling tired or weak, headache, shaking chills along with high temperature fevernausea, and muscle aches mood changes, feeling irritable.

Rebetol - question

Rum: Robert Koch Small. Five bundles received levothyroxine sodium, three with suicidal hypothyroidism and two with benign TSH elevations. The re-treatment scant virologic response rates by baseline plants are secreted in Table Monitoring In vitro fertilization of hepatitis C virus to ribavirin has been added, but failed resistance to ribavirin adhere originally defined. Additionally, due to the world of bacterial adverse effects, extreme care must be taken to date pregnancy in female mice receiving Rebetol and mental disorders of male hormones. Figure 1: Structural Formula. Show: Asymmetric Unit Biological Assembly. Main article: Taribavirin. Ribavirin may be added to direct-acting antiviral DAA therapy in people that have severe hepatic impairment decompensated cirrhosis or in people who have certain resistance mutations that make the DAA less effective. Significant teratogenic and embryocidal effects have been demonstrated in all animal species exposed to ribavirin. Anemia has been associated with worsening of heart problems, and in rare cases can cause a heart attack and death. It is chemically classified as a nucleoside analog because the structure of Ribavirin resembles the structure of the nucleoside guanosine. Use the dosing syringe provided, or use a medicine dose-measuring device not a kitchen spoon. Similarly, azathioprine an immunosuppressive cannot be used due to increased concentrations of azathioprine. Taribavirin, however, has useful properties of less erythrocyte-trapping and better liver-targeting than ribavirin. Ribavirin PDB 4pb1.
Common use

Main component of antiviral drug Rebetol is Ribavirin. It is used in combination with interferon drugs Intron A or PEG-Intron to treat chronic hepatitis C. Rebetol inhibits the replication of new virions, selectively inhibits synthesis of viral RNA, it does not suppress synthesis of RNA in a normal cells. Rebetol is the most effective against: herpes simplex virus, virus of smallpox, influenza viruses A and B, paramyxovirus (parainfluenza, mumps, Newcastle disease), reovirus, oncogenic RNA viruses.

Dosage and direction

Make sure you drink plenty of water while taking Rebetol, especially with your first intakes of the medication. Treatment continues for 24-48 weeks. To treat hepatitis C take Rebetol orally with food and full glass of water. Do not chew the tablet, swallow it whole. Recommended dose of Rebetol is 1-1.2 g a day divided in two for morning and evening intakes.


Rebetol is may cause a significant risk of serious harm to developing infants and abnormalities in a man's sperm, be very attentive using contraception medications. At least two forms of birth control during treatment and for six months afterwards are required.


Rebetol is contraindicated in patients hypersensitive to the components of Rebetol, in pregnant and breastfeedign women, in patients with chronic heart failure, myocardial infarction, kidney or liver failure, severe anemia, decompensated cirrhosis, autoimmune diseases, incurable thyroid disease, severe depression with suicidal intentions, children and adolescents under 18. Cautiousness should be exercised in patients with decompensated diabetes mellitus, pulmonary embolism, heart failure, thyroid disease (including hyperthyroidism), impaired clotting, thrombophlebitis, myelosuppression, haemoglobinopathy (thalassemia, sickle cell anemia), depression, suicidality (also in history).

Possible side effect

The most serious adverse reaction to Rebetol is anemia. Other side effects include: blood disorders, fever, hair loss, depression, fatigue, headache, insomnia, irritability, nausea, shortness of breath, joint or muscle pain, weight loss. Notify your doctor immediately if you experience any serious manifestation of the side effects listed above.

Drug interaction

Concomitant use with other antiviral drugs such as zidovudine (Retrovir), zalcitabine (Hivid) or stavudine (Zerit), may cause lactic acidosis. Medications which contain Mg2+ Г‰ Al3+, and also simethicone decrease absorption of Retrovir. Retrovir suppresses effects of zidovudine. In the patients with HIV infection concomitant treatment with Retrovir, zidovudine and stavudine leads to HIV viremia (a condition where viruses get into the bloodstream and can affect the rest of the body) and requires change of treatment.

Missed dose

Never take a double dose of this medication. If it is almost time of the next dose just skip the missed portion and continue to take the medicine according to the schedule.


If you suppose that took too much of this medication seek immediate medical attention. There is no information about adverse effects of Rebetol overdose.


Rebetol should be stored at room temperature between 2-8 C (36-46 F).


We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
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